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PinkMonkey Online Study Guide-Biology

8. 3 Replication Of DNA In Eukaryotes

Definition: "The process by which DNA produces daughter DNA molecules which are exact copies of the original DNA is called replication of DNA."

In eukaryotes, DNA is double stranded. The two strands are complementary to each other because of their base sequences.

Semi-conservative method of DNA replication

Important points:

(i) This is the most common method of DNA replication.

(ii) It takes place in the nucleus where the DNA is present in the chromosomes.

(iii) Replication takes place in the S-phase (synthesis phase) of the interphase nucleus.

(iv) The deoxyribose nucleotides needed for the formation of  the new DNA strands are present in the nucleoplasm.

At the time of replication, the two strands of DNA first separate. Each strand then acts as a template for the formation of a new strand. A new strand is constructed on each old strand, and two exactly identical double stranded DNA molecules are formed. In each new DNA molecule, one strand is old (original) while the other is newly formed. Hence, Watson and Crick described this method as semi-conservative replication.

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(A) An overall process of DNA replication showing replication fork and formation of new strands template and lagging template

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Figure 8.6 Stages in the semi-conservative method of DNA replication in eukaryotes

Table of Contents

8.0 Introduction
8.1 Packaging of Hereditary Material
8.2 The Structure of DNA
8.3 Replication Of DNA In Eukaryotes
8.4 Replicatin of Pokaryotic Chromosome
8.5 Plasmids
8.6 RNA: Structure and Types
8.7 The Genetic Code
8.8 The Central Theme of Protein Synthesis

Chapter 9


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